Hydrogen & Parkinson's Disease

Ohno K, Hirayama M, Ito M, Minato T, Yoritaka A, LeBaron T. Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease. Medical Gas Research. 2018;8(4):144. doi:https://doi.org/10.4103/2045-9912.248264

Chen W, Zhang HT, Qin SC. Neuroprotective Effects of Molecular Hydrogen: A Critical Review. Neuroscience Bulletin. 2020;37(3):389-404. doi:https://doi.org/10.1007/s12264-020-00597-1

Yoritaka A, Kobayashi Y, Hayashi T, Saiki S, Hattori N. Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study. Neurological Sciences. Published online July 28, 2021. doi:https://doi.org/10.1007/s10072-021-05489-4

Fu Y, Ito M, Fujita Y, et al. Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson’s disease. Neuroscience Letters. 2009;453(2):81-85. doi:https://doi.org/10.1016/j.neulet.2009.02.016

Fujita K, Nakabeppu Y, Noda M. Therapeutic Effects of Hydrogen in Animal Models of Parkinson’s Disease. Parkinson’s Disease. 2011;2011:1-9. doi:https://doi.org/10.4061/2011/307875

Nascimento GC, Santos BM, Pedrazzi JF, et al. Effects of hydrogen gas inhalation on L-DOPA-induced dyskinesia. Brain, Behavior, & Immunity - Health. 2023;30:100623. doi:https://doi.org/10.1016/j.bbih.2023.100623

Wu C, Zou P, Feng S, et al. Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders. Molecular Neurobiology. 2022;60(4):1749-1765. doi:https://doi.org/10.1007/s12035-022-03175-w