Molecular Hydrogen Benefits Kidney Health

Molecular Hydrogen Benefits Kidney Health

Exciting new research findings: Molecular Hydrogen & Kidney Health

At H Fizz, we are passionate about bringing the incredible benefits of molecular hydrogen to everyone. One of the most exciting areas of research is the positive impact of molecular hydrogen on kidney health:

What is Molecular Hydrogen?

Molecular hydrogen (H2) is a small, colorless, and tasteless molecule that acts as a powerful antioxidant. It has the unique ability to reduce oxidative stress and inflammation in the body, which are key factors in many diseases, including those affecting the kidneys.

Latest 2024 published Scientific Paper:

A scientific paper published in Medical Gas Research in 2024 [1] discusses the therapeutic effect of hydrogen and its mechanisms in kidney disease treatment. Below is a summary:

Clinical Evidence Supporting Hydrogen Use

Research, including animal and human studies, suggests that hydrogen can slow the progression of chronic kidney disease (CKD) and improve outcomes by reducing oxidative stress, inflammation, and supporting mitochondrial function [1]

  1. Reduces Oxidative Stress:
  • H2 acts as an antioxidant, reducing harmful molecules like hydroxyl radicals and peroxynitrite. 
  • Hydrogen increases the production of antioxidant enzymes such as Nrf2/ARE, SOD, CAT, GSH, and HO-1, which help protect the kidneys from oxidative stress.
  • This helps protect kidney cells from damage and slows down the progression of kidney d
  1. Lowers Inflammation:
  • H2 decreases inflammation in the kidneys by decreasing the levels of certain proteins that cause inflammation, such as TNF-α, NF-kB, IL-1β, IL-6, IL-8, and IL-10, which is crucial for preventing further da
  1. Protects Against Cell Death:
  • Molecular hydrogen helps prevent various types of cell death, including apoptosis (programmed cell death), autophagy (cell recycling), ferroptosis (iron-dependent cell death), and pyroptosis (inflammatory cell death).
  • This ensures the survival and proper functioning of kidney cells.
  1. Supports Mitochondrial Health:
  • H2 helps maintain healthy mitochondria, which are the powerhouses of cells.
  • Healthy mitochondria are vital for energy production and cell survival in the kidneys.
  • Studies show that hydrogen can help mitochondria function better, which is crucial for conditions like diabetic kidney disease (DKD). Better mitochondrial function helps slow down kidney disease.
  1. Improves Kidney Function:
  • Studies have shown that drinking hydrogen-rich water (HRW) improves blood flow and filtration rates in the kidneys.
  • It helps in reducing the formation of harmful molecules and supports better overall kidney function​.
  1. Balances the Immune System:
  • It helps keep the immune system balanced by reducing the release of substances that can cause more damage in kidney diseases.

 The paper also describes various ways patients with kidney issues can utilize molecular hydrogen (H2) for therapeutic benefits. Here are the main methods:

  1. Hydrogen-Rich Water (HRW): Drinking water enriched with molecular hydrogen is a practical and portable method for delivering H2. HRW has been shown to reduce oxidative stress, inflammation, and fibrosis in kidney tissues. It is particularly effective in conditions like oxalate-induced kidney injury, commonly associated with kidney stones.
2. Inhalation of Hydrogen Gas: Inhaling hydrogen gas is another effective way to deliver molecular hydrogen. Studies have demonstrated that inhaling H2 can alleviate kidney damage by reducing oxidative stress and inflammation. This method has been used in preclinical trials.
molecular hydrogen therapy
3. Hydrogen-Enriched Saline: This involves administering saline solution enriched with hydrogen. It has been shown to improve tissue and organ damage by reducing inflammation and oxidative stress. This method could be useful in acute kidney injury and other inflammatory kidney diseases.

These methods leverage the antioxidant, anti-inflammatory, and anti-apoptotic properties of molecular hydrogen to protect and improve kidney function. Future large-scale clinical studies are needed to fully confirm and optimize these treatments for broader clinical use

Electrolyzed Hydrogen Water (EHW) and Kidney Disease:

A 2024 Japanese research paper [1] describes the use of Electrolyzed Hydrogen Water for the Management of Chronic Kidney Disease and Dialysis Treatment, below is a summary:

  1. Electrolyzed hydrogen water (EHW) helps protect kidney cells by reducing oxidative stress and inflammation.
  2. It improves kidney function, including better blood flow and filtration rates.
  3. EHW supports mitochondrial health and reduces the formation of harmful molecules.
  4. Clinical studies show EHW benefits CKD patients by lowering kidney damage and improving overall kidney health during dialysis.

 

Having looked at the recent scientific evidence of how molecular hydrogen may benefit kidney health, Let's look at some easy steps to better kidney health with H Fizz:

  • Drink Hydrogen-Rich Water
  • Inhale Hydrogen

Why H Fizz?

At H Fizz, our products are designed to deliver the maximum benefits of molecular hydrogen in a convenient and effective way. Whether you are looking to support your kidney health or improve your overall well-being, our hydrogen products can help you achieve your health goals.

Visit our online store today to learn more about our products and how they can benefit you.

Hfizz.com

Sources:

1.   Cheng J, Shi M, Sun X, Lu H. Therapeutic effect of hydrogen and its mechanisms in kidney disease treatment. Medical Gas Research. 2024;14(2):48. doi:https://doi.org/10.4103/2045-9912.378880

 2.  Nakayama M, Kabayama S, Miyazaki M. Application of Electrolyzed Hydrogen Water for Management of Chronic Kidney Disease and Dialysis Treatment—Perspective View. Antioxidants. 2024;13(1):90. doi:https://doi.org/10.3390/antiox13010090

 

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